What Kineret contains
The active substance is anakinra. Each pre-filled syringe contains 100 mg of anakinra.
The other ingredients are:
sodium citrate, sodium chloride, disodium edetate, polysorbate 80 and sodium hydroxide and water for injections.
What Kineret looks like and contents of the pack
Kineret is a clear, colourless-to-white solution for injection and is supplied ready for use in a pre-filled syringe. It may contain some translucent-to-white particles of protein. The presence of these particles does not affect the quality of the product.
Pack sizes of 1, 7 or 28 pre-filled syringes.
Not all pack sizes may be marketed.
Biovitrum AB (publ)
SE-112 76 Stockholm
Marketing Authorisation Holder:
Biovitrum AB (publ)
SE-112 76 Stockholm
This leaflet was last approved in
Information on how to give yourself an injection of Kineret
This section contains information on how to give yourself an injection of Kineret. It is important that you do not try to give yourself the injection unless you have received training from your doctor, nurse or pharmacist. If you have questions about how to inject, please ask your doctor, nurse or pharmacist for assistance.
How do you or the person injecting you, use the Kineret pre-filled syringe?
You will need to give yourself an injection at the same time every day. Kineret is injected just under the skin. This is called a subcutaneous injection.
To give yourself a subcutaneous injection you will need:
a new pre-filled syringe of Kineret and
alcohol wipes or similar.
What should you do before you give yourself a subcutaneous injection of Kineret?
1. Take your Kineret pre-filled syringe out of the refrigerator.
2. Do not shake the pre-filled syringe.
3. Check the expiry date on the pre-filled syringe label (EXP). Do not use it if the date has passed the last day of the month shown.
4. Check the appearance of Kineret. It must be a clear, colourless-to-white solution. There may be some translucent-to-white particles of protein in the solution. The presence of these particles does not affect the quality of the product. The solution should not be used if it is discoloured or cloudy, or if any particles other than translucent-to-white particles are present.
5. For a more comfortable injection, leave at room temperature for approximately 30 minutes or hold the pre-filled syringe gently in your hand for a few minutes. Do not warm Kineret in any other way (for example, do not warm it in a microwave or in hot water).
6. Do not remove the cover from the syringe until you are ready to inject.
7. Wash your hands thoroughly.
8. Find a comfortable, well-lit, clean surface and put all the equipment you need within reach.
How do you prepare your Kineret injection?
Before you inject Kineret you must do the following:
1. Hold the syringe barrel and gently take the cover from the needle without twisting. Pull straight as shown in pictures 1 and 2. Do not touch the needle or push the plunger. 2. You may notice a small air bubble in the pre-filled syringe. You do not have to remove the air bubble before injecting. Injecting the solution with the air bubble is harmless.
3. You can now use the pre-filled syringe.
Where should you give your injection?
The most suitable places to inject yourself are the top of your thighs and the abdomen, except for the area around the navel. Change the place that you inject each time so you dont become sore in one area. If someone else is injecting for you, they can also use the back of your arms.
How do you give your injection?
1. Disinfect your skin by using the alcohol wipe and pinch the skin between your thumb and forefinger, without squeezing it.
2. Put the needle fully into the skin as shown by your nurse or doctor.
3. Pull slightly on the plunger to check that a blood vessel has not been punctured. If you see blood in the syringe, remove the needle and re-insert it in another place.
4. Inject the liquid slowly and evenly, always keeping your skin pinched.
5. After injecting the liquid, remove the needle and let go of your skin.
6. Only use each syringe for one injection.
If you have any problems, please do not be afraid to ask your doctor or nurse for help and advice.
Disposing of used syringes
Do not put the cover back on used needles.
Keep used syringes out of reach and sight of children
Never put the pre-filled syringes that you have used into your normal household rubbish bin.
The used pre-filled syringe should be disposed of in accordance with local requirements. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.